Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling

@article{Pandian2015MetastaticNC,
  title={Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling},
  author={V. Pandian and S. Ramraj and F. H. Khan and Tasfia Azim and N. Aravindan},
  journal={Stem Cell Research \& Therapy},
  year={2015},
  volume={6}
}
IntroductionHigh-risk neuroblastoma (HR-NB) presenting with hematogenous metastasis is one of the most difficult cancers to cure. Patient survival is poor. Aggressive tumors contain populations of rapidly proliferating clonogens that exhibit stem cell properties, cancer stem cells (CSCs). Conceptually, CSCs that evade intensive multimodal therapy dictate tumor progression, relapse/recurrence, and poor clinical outcomes. Herein, we investigated the plasticity and stem-cell related molecular… Expand
Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors
Epithelial plasticity and metastatic cascade
  • Minal Garg
  • Biology, Medicine
  • Expert opinion on therapeutic targets
  • 2018
Neuroblastoma Origin and Therapeutic Targets for Immunotherapy
Neural crest and cancer: Divergent travelers on similar paths
Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma
...
1
2
...

References

SHOWING 1-10 OF 57 REFERENCES
400 Page 12 of 13 http://stemcellres.com/content
  • Stem Cell Research & Therapy
  • 2015
Lancet
Cell plasticity and heterogeneity in cancer.
Constitutive expression and activation of stress response genes in cancer stem-like cells/tumour initiating cells: Potent targets for cancer stem cell therapy
  • T. Torigoe, Y. Hirohashi, Kazuyo Yasuda, N. Sato
  • Biology, Medicine
  • International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • 2013
...
1
2
3
4
5
...