Metastatic bone disease: clinical and therapeutic aspects.

  title={Metastatic bone disease: clinical and therapeutic aspects.},
  author={J. J. Body},
  volume={13 Suppl 1},
Breast and prostate carcinomas are the tumors most commonly associated with skeletal metastases, and the skeleton is the most common site of metastatic disease and of first distant relapse in breast cancer. Bone metastases are the source of considerable morbidity, including pain and functional disability, fractures, hypercalcemia, and epidural compression. The classical radionuclide bone scan remains the most effective tool for the screening of metastatic bone disease, but X-rays are more… CONTINUE READING


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