Metastatic Salivary Gland Tumors: A Single-Center Study Demonstrating the Feasibility and Potential Clinical Benefit of Molecular-Profiling-Guided Therapy

@inproceedings{Popovtzer2015MetastaticSG,
  title={Metastatic Salivary Gland Tumors: A Single-Center Study Demonstrating the Feasibility and Potential Clinical Benefit of Molecular-Profiling-Guided Therapy},
  author={Aron Popovtzer and Michal Sarfaty and Dror Limon and Gideon Marshack and Eli Perlow and Addie Dvir and Lior Soussan-Gutman and Salomon Marcello Stemmer},
  booktitle={BioMed research international},
  year={2015}
}
We evaluated the use of molecular profiling (MP) for metastatic salivary gland adenoid cystic carcinoma (SACC), for which there is no standard treatment. MP (Caris Molecular Intelligence) was performed on biopsy samples from all metastatic SACC patients attending a tertiary medical center between 2010 and 2013 (n = 14). Treatment was selected according to the biomarkers identified. Findings were compared with all similarly diagnosed patients treated in the same center between 1996 and 2009 (n… CONTINUE READING