Metastasizing of human melanoma on immunodeficient mice. Tumor cells in the circulation

Abstract

The subline Bro of human melanoma xenograft with a high metastasizing activity is studied. The data obtained by flow fluorometry after staining with tumor-specific monoclonal antibodies indicate that free melanoma cells are present in the peripheral blood of animals; the largest number of these cells is found in mice with combined immunodeficiencies (beige… (More)
DOI: 10.1007/BF02444456

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