Metastasis-associated long non-coding RNA drives gastric cancer development and promotes peritoneal metastasis.

@article{Okugawa2014MetastasisassociatedLN,
  title={Metastasis-associated long non-coding RNA drives gastric cancer development and promotes peritoneal metastasis.},
  author={Yoshinaga Okugawa and Yuji Toiyama and Keun Hur and Shusuke Toden and Susumu Saigusa and Koji Tanaka and Yasuhiro Inoue and Yasuhiko Mohri and Masato Kusunoki and Clement Richard Boland and Ajay Goel},
  journal={Carcinogenesis},
  year={2014},
  volume={35 12},
  pages={2731-9}
}
The prognosis of gastric cancer (GC) patients with peritoneal dissemination remains poor, and a better understanding of the underlying mechanisms is critical for the development of new treatments that will improve survival in these patients. This study aimed to clarify the clinical and biological role of two key metastasis-associated long non-coding RNAs (lncRNAs) in GC. We analyzed the expression levels of two lncRNAs-Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) and HOX… CONTINUE READING