• DOI:10.1007/s13258-016-0453-z
Corpus ID: 1041564

Metastasis associated genomic aberrations in stage II rectal cancer

@article{Zhao2016MetastasisAG,
  title={Metastasis associated genomic aberrations in stage II rectal cancer},
  author={H. Zhao and Zhi-Zhou Shi and Rui Jiang and D. Zhao and Hai-tao Zhou and J. Liang and Xin-yu Bi and J. Zhao and Z. Li and J. Zhou and Z. Huang and Y. Zhang and J. Wang and X. Xu and Y. Cai and M. Wang},
  journal={Genes & Genomics},
  year={2016},
  volume={38},
  pages={1085-1094}
}

H. Zhao, Zhi-Zhou Shi, +14 authors Y. Zhang

Published 2016

Biology

Genes & Genomics

Genomic aberrations of rectal carcinoma, especially DNA copy number changes associated with metastasis were largely unclear. We aim to identify the metastasis associated biomarkers in stage II rectal cancer. Formalin-fixed, paraffin-embedded primary tumor tissues of stage II rectal carcinoma were analyzed by array-based comparative genomic hybridization, and genomic aberrations were identified by Genomic Workbench and SAM software. Copy number changes and mRNA expressions were validated by Real… CONTINUE READING

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