Metastasis associated genomic aberrations in stage II rectal cancer

  title={Metastasis associated genomic aberrations in stage II rectal cancer},
  author={H. Zhao and Zhi-Zhou Shi and Rui Jiang and D. Zhao and Hai-tao Zhou and J. Liang and Xin-yu Bi and J. Zhao and Z. Li and J. Zhou and Z. Huang and Y. Zhang and J. Wang and X. Xu and Y. Cai and M. Wang},
  journal={Genes & Genomics},
  • H. Zhao, Zhi-Zhou Shi, +14 authors Y. Zhang
  • Published 2016
  • Biology
  • Genes & Genomics
  • Genomic aberrations of rectal carcinoma, especially DNA copy number changes associated with metastasis were largely unclear. We aim to identify the metastasis associated biomarkers in stage II rectal cancer. Formalin-fixed, paraffin-embedded primary tumor tissues of stage II rectal carcinoma were analyzed by array-based comparative genomic hybridization, and genomic aberrations were identified by Genomic Workbench and SAM software. Copy number changes and mRNA expressions were validated by Real… CONTINUE READING
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