Metastasis Awakening: Targeting dormant cancer

@article{AguirreGhiso2013MetastasisAT,
  title={Metastasis Awakening: Targeting dormant cancer},
  author={Julio A. Aguirre-Ghiso and Paloma Bragado and Mar{\'i}a Soledad Garc{\'i}a Sosa},
  journal={Nature Medicine},
  year={2013},
  volume={19},
  pages={276-277}
}
An important challenge for oncologists is to treat overt metastasis, the major source of cancer-related deaths1. Adjuvant therapy should prevent distant recurrences by targeting residual disseminated tumor cells (DTCs) that give origin to metastasis, as well as existing undetected micrometastasis. Whereas in some cases, such as breast cancer, patients can show delayed metastasis after hormonal therapies (for example, in estrogen receptor–positive tumors) or treatment with trastuzumab, for HER2… CONTINUE READING
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nature medicine volume 19 | number 3 | marCH 2013

M. S. Sosa, A. Avivar-Valderas, P. Bragado, H. C. Wen, J. A. Aguirre-Ghiso
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