Metapopulation concepts applied to falciparum malaria and their impacts on the emergence and spread of chloroquine resistance.

@article{Ariey2003MetapopulationCA,
  title={Metapopulation concepts applied to falciparum malaria and their impacts on the emergence and spread of chloroquine resistance.},
  author={Fr{\'e}d{\'e}ric Ariey and Jean-Bernard Duchemin and Vincent Robert},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2003},
  volume={2 3},
  pages={185-92}
}
Studying the structure of metapopulations is a new concept in population genetics of infectious diseases that is particularly adapted to the analysis of parasite populations. We considered one application of this theory focusing on Plasmodium falciparum populations. Our study consisted of three main steps: the relevance of the approach, the proposal of a simplified model using metapopulation concepts, and the exploration of the consequences on antimalarial drug resistance. Our main result… CONTINUE READING

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