Metaplasticity of horizontal connections in the vicinity of focal laser lesions in rat visual cortex.

@article{Imbrosci2010MetaplasticityOH,
  title={Metaplasticity of horizontal connections in the vicinity of focal laser lesions in rat visual cortex.},
  author={Barbara Imbrosci and Ulf T. Eysel and Thomas Mittmann},
  journal={The Journal of physiology},
  year={2010},
  volume={588 Pt 23},
  pages={
          4695-703
        }
}
Focal cortical injuries are accompanied by a reorganization of the adjacent neuronal networks. An increased synaptic plasticity has been suggested to mediate, at least in part, this functional reorganization. Previous studies showed an increased long-term potentiation (LTP) at synapses formed by ascending fibres projecting onto layers 2/3 pyramidal cells following lesions in rat visual cortex. This could be important to establish new functional connections within a vertical cortical column… CONTINUE READING

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