Metaplasia--a transdifferentiation process that facilitates cancer development: the model of gastric intestinal metaplasia.

@article{Mesquita2006MetaplasiaaTP,
  title={Metaplasia--a transdifferentiation process that facilitates cancer development: the model of gastric intestinal metaplasia.},
  author={Patricia Lagun Mesquita and Almeida Raquel and Lunet Nuno and Celso A Reis and Luis Filipe dos Santos Silva and Jacinta Serpa and Isabelle Van Seuningen and H. E. Ambassador Cristi{\'a}n Barros and Leonor David},
  journal={Critical reviews in oncogenesis},
  year={2006},
  volume={12 1-2},
  pages={3-26}
}
Metaplasia, in general, and intestinal metaplasia, in particular, are transdifferentiation processes triggered by environmental aggressions. The heterogeneity of different morphologic variants of metaplasia and distinction from close morphologic entities--heterotopia and hamartoma--is reviewed. Recent data on the characterization of the molecular and… CONTINUE READING