Metamorphosis of Borrelia burgdorferi organisms--RNA, lipid and protein composition in context with the spirochetes' shape.

@article{AlRobaiy2010MetamorphosisOB,
  title={Metamorphosis of Borrelia burgdorferi organisms--RNA, lipid and protein composition in context with the spirochetes' shape.},
  author={Samiya Al-Robaiy and Hassan Dihazi and Johannes Kacza and Johannes Seeger and J{\"u}rgen Schiller and Daniel Huster and Jens Knauer and Reinhard Konrad Straubinger},
  journal={Journal of basic microbiology},
  year={2010},
  volume={50 Suppl 1},
  pages={S5-17}
}
Borrelia burgdorferi, the agent of Lyme borreliosis, has the ability to undergo morphological transformation from a motile spirochetal to non-motile spherical shape when it encounters unfavorable conditions. However, little information is available on the mechanism that enables the bacterium to change its shape and whether major components of the cells--nucleic acids, proteins, lipids--are possibly modified during the process. Deducing from investigations utilizing electron microscopy, it seems… CONTINUE READING