Metamodeling tumor-immune system interaction, tumor evasion and immunotherapy

@article{dOnofrio2008MetamodelingTS,
  title={Metamodeling tumor-immune system interaction, tumor evasion and immunotherapy},
  author={Alberto d'Onofrio},
  journal={Mathematical and Computer Modelling},
  year={2008},
  volume={47},
  pages={614-637}
}
The tumor–immune system competitive interaction is very complex, being nonlinear and, to some extent, evolutive. Furthermore, the tumor itself is not a single well defined disease, but, more correctly, a wide family of diseases, characterized by some important common features, but also by many great differences between them. For this reason, we introduced in [A. d’Onofrio, A general framework for modeling tumor–immune system competition and immunotherapy: Mathematical analysis and biomedical… CONTINUE READING
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