Metals, oxidative stress and neurodegenerative disorders

@article{Jomov2010MetalsOS,
  title={Metals, oxidative stress and neurodegenerative disorders},
  author={K. Jomov{\'a} and D. Vondrakova and M. Lawson and M. Valko},
  journal={Molecular and Cellular Biochemistry},
  year={2010},
  volume={345},
  pages={91-104}
}
The neurodegenerative diseases, Alzheimer’s disease (AD) and Parkinson’s disease (PD), are age-related disorders characterized by the deposition of abnormal forms of specific proteins in the brain. AD is characterized by the presence of extracellular amyloid plaques and intraneuronal neurofibrillary tangles in the brain. Biochemical analysis of amyloid plaques revealed that the main constituent is fibrillar aggregates of a 39–42 residue peptide referred to as the amyloid-β protein (Aβ). PD is… Expand
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References

SHOWING 1-10 OF 136 REFERENCES
Chemistry and biochemistry of oxidative stress in neurodegenerative disease.
Copper in the brain and Alzheimer’s disease
Redox imbalance in Parkinson's disease.
Oxidative stress and antioxidant therapy in Parkinson's disease
The redox chemistry of the Alzheimer's disease amyloid β peptide
Vitamin E in Neurodegenerative Disorders: Alzheimer's Disease
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
The metallobiology of Alzheimer's disease
  • A. Bush
  • Biology, Medicine
  • Trends in Neurosciences
  • 2003
...
1
2
3
4
5
...