Metalloproteinase-3 and -9 as novel markers in the evaluation of ulcerative colitis activity in children.

@article{KoflaDubacz2014Metalloproteinase3A,
  title={Metalloproteinase-3 and -9 as novel markers in the evaluation of ulcerative colitis activity in children.},
  author={Anna Kofla-Dłubacz and Małgorzata Matusiewicz and Elżbieta Krzesiek and Leszek Noga and Barbara Iwańczak},
  journal={Advances in clinical and experimental medicine : official organ Wroclaw Medical University},
  year={2014},
  volume={23 1},
  pages={103-10}
}
OBJECTIVES The enhanced activity of matrix endopeptidases (MMPs) involved in the degradation of connective tissue has been noted in tissue samples from the digestive tract in inflammatory bowel disease (IBD), however sera concentrations of MMPs, a potential tool for diagnostic tests in IBD patients, have not been established so far. The goal of the studies was to evaluate the concentrations of MMP-3 and MMP-9, in the sera of children suffering from ulcerative colitis (UC) in relation to disease… CONTINUE READING

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