Metalloproteases and the degradome.

@article{Ugalde2010MetalloproteasesAT,
  title={Metalloproteases and the degradome.},
  author={Alejandro Pi{\~n}eiro Ugalde and Gonzalo R. Ord{\'o}{\~n}ez and Pedro M Quiros and Xose S. Puente and Carlos L{\'o}pez-Ot{\'i}n},
  journal={Methods in molecular biology},
  year={2010},
  volume={622},
  pages={
          3-29
        }
}
Metalloproteases comprise a heterogeneous group of proteolytic enzymes whose main characteristic is the utilization of a metal ion to polarize a water molecule and perform hydrolytic reactions. These enzymes represent the most densely populated catalytic class of proteases in many organisms and play essential roles in multiple biological processes. In this chapter, we will first present a general description of the complexity of metalloproteases in the context of the degradome, which is defined… CONTINUE READING
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