Metallobiochemistry of RNA. Co(NH3)6(3+) as a probe for Mg2+(aq) binding sites.

@article{Cowan1993MetallobiochemistryOR,
  title={Metallobiochemistry of RNA. Co(NH3)6(3+) as a probe for Mg2+(aq) binding sites.},
  author={James Allan Cowan},
  journal={Journal of inorganic biochemistry},
  year={1993},
  volume={49 3},
  pages={171-5}
}
Co(NH3)6(3+) may serve as a probe of outer sphere complexation by Mg(H2O)6(2+) with RNA. The number of metal binding sites may be quantitatively assessed by optical spectroscopy (55-130, depending on background [K+]). Novel coordination-induced features have been observed in circular dichroism spectra.