Metallo-beta-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme.

@article{Yan2001MetallobetalactamasesIC,
  title={Metallo-beta-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme.},
  author={J J Yan and Po Ren Hsueh and Wen Chien Ko and K. T. Luh and Sarai H Tsai and Henry M Wu and J. J. Wu},
  journal={Antimicrobial agents and chemotherapy},
  year={2001},
  volume={45 8},
  pages={2224-8}
}
A total of 209 clinical isolates of Pseudomonas (193 Pseudomonas aeruginosa, 10 P. putida, 4 P. stutzeri, and 2 P. fluorescens isolates) with reduced susceptibilities to imipenem and/or ceftazidime were subjected to PCR assays with primers specific for bla(IMP-1), bla(IMP-2), bla(VIM-1), and bla(VIM-2) and sequence analysis to identify the metallo-beta-lactamases (MBLs) prevalent among these organisms in Taiwan; and 21 isolates gave positive results. Five isolates including two P. putida and… CONTINUE READING

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