Metal homeostasis in bacteria: the role of ArsR–SmtB family of transcriptional repressors in combating varying metal concentrations in the environment

@article{Saha2017MetalHI,
  title={Metal homeostasis in bacteria: the role of ArsR–SmtB family of transcriptional repressors in combating varying metal concentrations in the environment},
  author={Rudra Prasad Saha and Saikat Samanta and Surajit Patra and Diganta Sarkar and Abinit Saha and Manoj Kumar Singh},
  journal={BioMetals},
  year={2017},
  volume={30},
  pages={459-503}
}
Bacterial infections cause severe medical problems worldwide, resulting in considerable death and loss of capital. With the ever-increasing rise of antibiotic-resistant bacteria and the lack of development of new antibiotics, research on metal-based antimicrobial therapy has now gained pace. Metal ions are essential for survival, but can be highly toxic to organisms if their concentrations are not strictly controlled. Through evolution, bacteria have acquired complex metal-management systems… CONTINUE READING