Metal fume fever: characterization of clinical and plasma IL-6 responses in controlled human exposures to zinc oxide fume at and below the threshold limit value.

@article{Fine1997MetalFF,
  title={Metal fume fever: characterization of clinical and plasma IL-6 responses in controlled human exposures to zinc oxide fume at and below the threshold limit value.},
  author={Jonathan M. Fine and Terry J. Gordon and Lung-chi Chen and Patricia Gale Kinney and Gianluca Falcone and William S. Beckett},
  journal={Journal of occupational and environmental medicine},
  year={1997},
  volume={39 8},
  pages={
          722-6
        }
}
Results from animal and preliminary human exposure studies have called into question whether the 5 mg/m3 8-hour time-weighted average threshold limit value (TLV) for zinc oxide fume is sufficient to protect workers against metal fume fever. The objectives of this study were to determine the clinical effects of exposures to low concentrations of zinc oxide and to ascertain whether these exposures elevated circulating levels of specific cytokines, which could account for the symptoms of the metal… CONTINUE READING
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