Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging.

  title={Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging.},
  author={Joanna Malicka and Ignacy Gryczyński and Chris D. Geddes and Joseph R. Lakowicz},
  journal={Journal of biomedical optics},
  volume={8 3},
Indocyanine green (ICG) is widely used in medical imaging and testing. Its complex spectral behavior and low quantum yield limits some applications. We show that proximity of ICG to a metallic silver particle increases its intensity approximately 20-fold and decreases the decay time. Since the rate of photobleaching is not increased, our results suggest that ICG-silver particle complexes can yield at least 20-fold more photons per ICG molecule for improved medical imaging. 

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Changes in susceptibility to acetaminophen-induced liver injury by the organic anion indocyanine green.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2001

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