Metal deposition and functional neurotoxicity in rats after 3-6 weeks nasal exposure by two physicochemical forms of manganese.

Abstract

Airborne manganese represents a major risk of nervous system damage first of all in industrial settings. The resulting effects may depend on the dose and physicochemical form of Mn. To compare the effect of soluble and nanoparticulate Mn, adult male rats received daily instillation of MnCl(2) solution or MnO(2) nanoparticle suspension (dose: 2.53mg Mn per… (More)
DOI: 10.1016/j.etap.2010.04.006

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