Metal-based anticancer chemotherapeutic agents.

@article{Muhammad2014MetalbasedAC,
  title={Metal-based anticancer chemotherapeutic agents.},
  author={Nafees Muhammad and Zijian Guo},
  journal={Current opinion in chemical biology},
  year={2014},
  volume={19},
  pages={144-53}
}
Since the discovery of the cisplatin antitumor activity, great efforts have focused on the rational design of metal-based anticancer agents that can be potentially used in cancer chemotherapy. Over the last four decades, a large number of metal complexes have been extensively investigated and evaluated in vitro and in vivo, and some of them were at different stages of clinical studies. Amongst these complexes, platinum (Pt(II) and Pt(IV)), ruthenium (Ru(II) and Ru(III)), gold (Au(I) and Au(III… CONTINUE READING
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Arene ruthenium dichloro complexes containing isonicotinic ester ligands: synthesis, molecular structure and cytotoxicity

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