Metal-based anticancer chemotherapeutic agents.

  title={Metal-based anticancer chemotherapeutic agents.},
  author={Nafees Muhammad and Zijian Guo},
  journal={Current opinion in chemical biology},
Since the discovery of the cisplatin antitumor activity, great efforts have focused on the rational design of metal-based anticancer agents that can be potentially used in cancer chemotherapy. Over the last four decades, a large number of metal complexes have been extensively investigated and evaluated in vitro and in vivo, and some of them were at different stages of clinical studies. Amongst these complexes, platinum (Pt(II) and Pt(IV)), ruthenium (Ru(II) and Ru(III)), gold (Au(I) and Au(III… CONTINUE READING
35 Citations
53 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 35 extracted citations


Publications referenced by this paper.
Showing 1-10 of 53 references

Arene ruthenium dichloro complexes containing isonicotinic ester ligands: synthesis, molecular structure and cytotoxicity

  • F-A Khan, B Therrien, G Süss-Fink, O Zava, PJ Dyson
  • J Organomet Chem
  • 2013

Similar Papers

Loading similar papers…