Metal Sensing by DNA.

@article{Zhou2017MetalSB,
  title={Metal Sensing by DNA.},
  author={Wenhu Zhou and Runjhun Saran and Juewen Liu},
  journal={Chemical reviews},
  year={2017},
  volume={117 12},
  pages={8272-8325}
}
Metal ions are essential to many chemical, biological, and environmental processes. In the past two decades, many DNA-based metal sensors have emerged. While the main biological role of DNA is to store genetic information, its chemical structure is ideal for metal binding via both the phosphate backbone and nucleobases. DNA is highly stable, cost-effective, easy to modify, and amenable to combinatorial selection. Two main classes of functional DNA were developed for metal sensing: aptamers and… CONTINUE READING
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