Metal Complexes Derived of Diosmin with Biological Activities in vitro

@article{Civa2019MetalCD,
  title={Metal Complexes Derived of Diosmin with Biological Activities in vitro},
  author={Ma{\'e}li M. F. Civa and Dirceu Aparecido Gonçalves de Souza and Renata G. Silva and D. D. S. A. Maciel and R. L. Tranquilin and S. Diniz and C. E. Okuyama and Marcio L. Santos and Regina Mara Silva Pereira},
  journal={Journal of Materials Science Research},
  year={2019},
  volume={9},
  pages={10}
}
The coordination of metal ions with flavonoids is applied to improve its pharmacological properties. To evaluate the role of ions on diosmin new complexes with Fe(II), Cu(II) and Co(II) ions were synthetized and characterized by UV, FT-IR and XRD techniques and surface morphology by SEM. The biological activity of coordination complexes in vitro, the antioxidant (ABTS), antibacterial (disc diffusion and MIC) and antitumoral activities (MTT) were analyzed. Diosmin when reacting with Fe(II) at… Expand

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