Metagenomics for Mining New Genetic Resources of Microbial Communities

  title={Metagenomics for Mining New Genetic Resources of Microbial Communities},
  author={Manuel Ferrer and Ana Beloqui and Kenneth N. Timmis and Peter N. Golyshin},
  journal={Journal of Molecular Microbiology and Biotechnology},
  pages={109 - 123}
Recent progress has revealed that the capture of genetic resources of complex microbial communities in metagenome libraries allows the discovery of a richness of new enzymatic diversity that had not previously been imagined. Activity-based screening of such libraries has demonstrated that this new diversity is not simply variations on known sequence themes, but rather the existence of entirely new sequence classes and novel functionalities. This new diversity, the surface of which has thus far… 

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