Metagenomic analysis of the canine oral cavity as revealed by high-throughput pyrosequencing of the 16S rRNA gene.

@article{Sturgeon2013MetagenomicAO,
  title={Metagenomic analysis of the canine oral cavity as revealed by high-throughput pyrosequencing of the 16S rRNA gene.},
  author={Amy Sturgeon and J W Stull and Marcio Carvalho da Costa and J Scott Weese},
  journal={Veterinary microbiology},
  year={2013},
  volume={162 2-4},
  pages={891-8}
}
Efficient characterization of the canine oral microbiome is critical for understanding the role of oral bacteria in health and for providing insight into early diagnosis and treatment strategies against periodontal disease. To date, characterization has been limited to cloning-based sequencing and conventional culture-based studies, which generally underestimate community diversity as a result of inherent biases in their methodologies. Pyrosequencing, a cloning- and culture-independent… CONTINUE READING
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