Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen

  title={Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen},
  author={Matthias Hess and Alexander Sczyrba and Rob Egan and Tae-Wan Kim and Harshal A. Chokhawala and Gary P. Schroth and Shujun J Luo and Douglas S. Clark and Feng Chen and Tao Zhang and Roderick Ian Mackie and Len A. Pennacchio and Susannah G. Tringe and Axel Visel and Tanja Woyke and Zhong Wang and Edward M. Rubin},
  pages={463 - 467}
Metagenomic sequencing of biomass-degrading microbes from cow rumen reveals new carbohydrate-active enzymes. The paucity of enzymes that efficiently deconstruct plant polysaccharides represents a major bottleneck for industrial-scale conversion of cellulosic biomass into biofuels. Cow rumen microbes specialize in degradation of cellulosic plant material, but most members of this complex community resist cultivation. To characterize biomass-degrading genes and genomes, we sequenced and analyzed… 

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Why don't ruminal bacteria digest cellulose faster?

  • P. Weimer
  • Biology, Medicine
    Journal of dairy science
  • 1996
In light of numerous proposals to improve microbial cellulose digestion in ruminants, it is instructive to examine the characteristics of these species that contribute to their superior cellulolytic capabilities and to identify the factors that prevent them from digesting cellulose even more rapidly.

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