Metagenomic Analysis of Nitrate-Reducing Bacteria in the Oral Cavity: Implications for Nitric Oxide Homeostasis

@inproceedings{Hyde2014MetagenomicAO,
  title={Metagenomic Analysis of Nitrate-Reducing Bacteria in the Oral Cavity: Implications for Nitric Oxide Homeostasis},
  author={Embriette R. Hyde and Fernando Andrade and Zalman Vaksman and Kavitha Parthasarathy and Hong Jiang and Deepa K. Parthasarathy and Ashley C. Torregrossa and Gena D. Tribble and Heidi B. Kaplan and Joseph F Petrosino and Nathan S. Bryan},
  booktitle={PloS one},
  year={2014}
}
The microbiota of the human lower intestinal tract helps maintain healthy host physiology, for example through nutrient acquisition and bile acid recycling, but specific positive contributions of the oral microbiota to host health are not well established. Nitric oxide (NO) homeostasis is crucial to mammalian physiology. The recently described entero-salivary nitrate-nitrite-nitric oxide pathway has been shown to provide bioactive NO from dietary nitrate sources. Interestingly, this pathway is… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2010
VIEW 1 EXCERPT

The human oral microbiome.

  • Journal of bacteriology
  • 2010
VIEW 1 EXCERPT

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