Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients

@inproceedings{Ojima2015MetagenomicAR,
  title={Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients},
  author={Masahiro Ojima and Daisuke Motooka and Kentaro Shimizu and Kazuyoshi Gotoh and Ayumi Shintani and Kazuhisa Yoshiya and Shota Nakamura and Hiroshi Ogura and Tetsuya Iida and Takeshi Shimazu},
  booktitle={Digestive Diseases and Sciences},
  year={2015}
}
Metagenomic analysis targeting the 16S rRNA gene has made it possible to characterize the vast array of microorganisms contained in the gut. The purpose of this study was to evaluate how gut microbiota change in intensive care unit (ICU) patients in the acute phase after admission. This prospective observational cohort study investigated 12 patients admitted to a single ICU of a large urban tertiary referral hospital. All patients were mechanically ventilated on admission. Fecal samples were… CONTINUE READING