Metadoxine in acute alcohol intoxication: a double-blind, randomized, placebo-controlled study.

@article{Shpilenya2002MetadoxineIA,
  title={Metadoxine in acute alcohol intoxication: a double-blind, randomized, placebo-controlled study.},
  author={Leonid S Shpilenya and Alexander P Muzychenko and Giovanni Battista Gasbarrini and Giovanni Addolorato},
  journal={Alcoholism, clinical and experimental research},
  year={2002},
  volume={26 3},
  pages={340-6}
}
BACKGROUND At present there are only intriguing and preliminary clinical results regarding the efficacy of metadoxine (pyridoxol L-2-pyrrolidone-5-carboxylate) in acute alcohol intoxication. The present study was planned with the aim of investigating the effectiveness of metadoxine in the management of patients affected by acute ethanol intoxication. METHODS A double-blind, randomized, multicenter, placebo-controlled trial was carried out on 58 patients of both sexes with acute ethanol… CONTINUE READING

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