Metachromatic Leukodystrophy Clinical, Biological and Therapeutic Aspects

Abstract

Scholz’s disease or metachromatic leukodystrophy (MLD) is a lysosomal storage disease caused by a deficiency in arylsulfatase A (ARSA: EC 3.1.6.8). This enzyme is responsible for the degradation of sulfatides commonly called cerebroside-3-sulfate or 3-O sulfogalactosylceramide in galactocerebroside and sulfate. The success of hydrolysis of these… (More)

Topics

3 Figures and Tables

Slides referencing similar topics