Metabotropic glutamate receptor-dependent long-term potentiation.

  title={Metabotropic glutamate receptor-dependent long-term potentiation.},
  author={Roger Anwyl},
  volume={56 4},
The induction of the most common form of LTP is well known to involve activation of N-methyl-D-aspartate receptors. However, considerable evidence has also shown that certain forms of LTP induction at excitatory synapses onto both principle cells and interneurons are dependent on activation of metabotropic glutamate receptors (mGluRs). mGluR-dependent LTP occurs in widespread areas of the brain including the neocortex, hippocampus, striatum and nucleus accumbens. mGluR-dependent forms of LTP… CONTINUE READING