Metabolomics of cancer.

  title={Metabolomics of cancer.},
  author={Natalie J. Serkova and Kristine Glunde},
  journal={Methods in molecular biology},
Metabolomics, one of the "omic" sciences in systems biology, is the global assessment and validation of endogenous small-molecule biochemicals (metabolites) within a biologic system. Initially, putative quantitative metabolic biomarkers for cancer detection and/or assessment of efficacy of anticancer treatment are usually discovered in a preclinical setting (using animal and human cell cultures), followed by translational validation of these biomarkers in biofluid or tumor tissue. Based on the… CONTINUE READING
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