Metabolomics approach for multibiomarkers determination to investigate dengue virus infection in human patients.

  title={Metabolomics approach for multibiomarkers determination to investigate dengue virus infection in human patients.},
  author={Nurul Shahfiza and Hasnah Osman and Tang Thean Hock and Abdel-Hamid Zaki Abdel-Hamid},
  journal={Acta biochimica Polonica},
  volume={64 2},
BACKGROUND Dengue is one of the major public health problems in the world, affecting more than fifty million cases in tropical and subtropical region every year. The metabolome, as pathophysiological end-points, provide significant understanding of the mechanism and progression of dengue pathogenesis via changes in the metabolite profile of infected patients. Recent developments in diagnostic technologies provide metabolomics for the early detection of infectious diseases. METHODS The mid… 

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