Metabolomics- and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii.

@article{May2008MetabolomicsAP,
  title={Metabolomics- and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii.},
  author={P. K. Garc{\'i}a May and Stefanie Wienkoop and Stefan Kempa and Bj{\"o}rn Usadel and Nils Christian and Jens Rupprecht and Julia Weiss and Luis Recuenco-Mu{\~n}oz and Oliver Ebenh{\"o}h and Wolfram Weckwerth and Dirk Walther},
  journal={Genetics},
  year={2008},
  volume={179 1},
  pages={
          157-66
        }
}
We present an integrated analysis of the molecular repertoire of Chlamydomonas reinhardtii under reference conditions. Bioinformatics annotation methods combined with GCxGC/MS-based metabolomics and LC/MS-based shotgun proteomics profiling technologies have been applied to characterize abundant proteins and metabolites, resulting in the detection of 1069 proteins and 159 metabolites. Of the measured proteins, 204 currently do not have EST sequence support; thus a significant portion of the… CONTINUE READING

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