Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool

@inproceedings{Brown2016MetabolomicsAM,
  title={Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool},
  author={Dustin G. Brown and Sangeeta Rao and Tiffany L. Weir and Joanne O’Malia and Marlon L. Bazan and Regina J. Brown and Elizabeth P Ryan},
  booktitle={Cancer & metabolism},
  year={2016}
}
BACKGROUND Colorectal cancers (CRC) are associated with perturbations in cellular amino acids, nucleotides, pentose-phosphate pathway carbohydrates, and glycolytic, gluconeogenic, and tricarboxylic acid intermediates. A non-targeted global metabolome approach was utilized for exploring human CRC, adjacent mucosa, and stool. In this pilot study, we identified metabolite profile differences between CRC and adjacent mucosa from patients undergoing colonic resection. Metabolic pathway analyses… CONTINUE READING
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