Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.

@article{Zhang2015MetabolomicsRT,
  title={Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.},
  author={Limin Zhang and Emmanuel Hatzakis and Robert G. Nichols and Ruixin Hao and Jared B Correll and Philip L. Smith and Christopher R Chiaro and Gary H. Perdew and Andrew D. Patterson},
  journal={Environmental science & technology},
  year={2015},
  volume={49 13},
  pages={8067-77}
}
Environmental exposure to dioxins and dioxin-like compounds poses a significant health risk for human health. Developing a better understanding of the mechanisms of toxicity through activation of the aryl hydrocarbon receptor (AHR) is likely to improve the reliability of risk assessment. In this study, the AHR-dependent metabolic response of mice exposed to 2,3,7,8-tetrachlorodibenzofuran (TCDF) was assessed using global (1)H nuclear magnetic resonance (NMR)-based metabolomics and targeted… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-2 of 2 references

cell-like and Foxp3(+) regulatory T cells

T regulatory
Nat. Immunol. 2010, • 2010

Similar Papers

Loading similar papers…