Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action.

@article{Xuan2011MetabolomicPT,
  title={Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action.},
  author={Jiekun Xuan and Guihua Pan and Yunping Qiu and Shi Lun Yang and Mingming Su and Yumin Liu and Jian Chen and Guoyin Feng and Yi-ru Fang and Wei Jia and Qinghe Xing and Lin He},
  journal={Journal of proteome research},
  year={2011},
  volume={10 12},
  pages={
          5433-43
        }
}
Despite recent advances in understanding the pathophysiology of schizophrenia and the mechanisms of antipsychotic drug action, the development of biomarkers for diagnosis and therapeutic monitoring in schizophrenia remains challenging. Metabolomics provides a powerful approach to discover diagnostic and therapeutic biomarkers by analyzing global changes in an individual's metabolic profile in response to pathophysiological stimuli or drug intervention. In this study, we performed gas… CONTINUE READING
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