Metabolomic analysis of the toxic effect of chronic exposure of cadmium on rat urine.

@article{Chen2018MetabolomicAO,
  title={Metabolomic analysis of the toxic effect of chronic exposure of cadmium on rat urine.},
  author={Shuai X. Chen and Meiyan Zhang and Lu Bo and Siqi Li and Liyan Hu and Xiujuan Zhao and Changhao Sun},
  journal={Environmental science and pollution research international},
  year={2018},
  volume={25 4},
  pages={3765-3774}
}
This study aimed to assess the toxic effect of chronic exposure to cadmium through a metabolomic approach based on ultra-performance liquid chromatography/mass spectrometry (UPLC-MS). Forty male Sprague-Dawley rats were randomly assigned to the following groups: control, low-dose cadmium chloride (CdCl2) (0.13 mg/kg body weight (bw)), middle-dose CdCl2 (0.8… CONTINUE READING