Metabolomic Derangements Are Associated with Mortality in Critically Ill Adult Patients


OBJECTIVE To identify metabolomic biomarkers predictive of Intensive Care Unit (ICU) mortality in adults. RATIONALE Comprehensive metabolomic profiling of plasma at ICU admission to identify biomarkers associated with mortality has recently become feasible. METHODS We performed metabolomic profiling of plasma from 90 ICU subjects enrolled in the BWH… (More)
DOI: 10.1371/journal.pone.0087538