Metabolome responses of the sea cucumber Apostichopus japonicus to multiple environmental stresses: Heat and hypoxia.

@article{Huo2019MetabolomeRO,
  title={Metabolome responses of the sea cucumber Apostichopus japonicus to multiple environmental stresses: Heat and hypoxia.},
  author={Da Huo and Lina Sun and Libin Zhang and Xiaoshang Ru and Shilin Liu and Hongsheng Yang},
  journal={Marine pollution bulletin},
  year={2019},
  volume={138},
  pages={
          407-420
        }
}
Economically important marine organisms face severe environmental challenges, such as high temperature and low dissolved oxygen, from global climate change. Adverse environmental factors impact the survival and growth of economically important marine organisms, thereby negatively influencing the aquaculture industry. However, little is known about the responses of sea cucumbers to combined environmental co-stressors till now. In this study, ultra-performance liquid chromatography (UPLC) was… Expand
Global-warming-caused changes of temperature and oxygen alter the proteomic profile of sea cucumber Apostichopus japonicus.
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Combined Effects of Elevated Temperature and Crude Oil Pollution on Oxidative Stress and Apoptosis in Sea Cucumber (Apostichopus japonicus, Selenka)
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Integrated Application of Transcriptomics and Metabolomics Reveals the Energy Allocation-Mediated Mechanisms of Growth-Defense Trade-Offs in Crassostrea gigas and Crassostrea angulata
  • Chaogang Wang, Ao Li, +4 authors Li Li
  • Frontiers in Marine Science
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Understanding the genetic basis of trait variations and their coordination between relative species or populations distributing in different environmental conditions is important in evolutionaryExpand
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Metabolomic responses of sea cucumber Apostichopus japonicus to thermal stresses
TLDR
The results showed that both temperatures disturbed energy metabolism and induced osmotic regulation based on the metabolic biomarkers such as elevated threonine, alanine, arginine, glutamate, tyrosine, histidine, glycine, fumarate, glucose, and AMP and decreased ATP, aspartate, hypotaurine, and choline after exposure for 0 days and 3 days. Expand
Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus: respiration, digestion, immunity and oxidative damage
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The physiological responses of Apostichopus japonicus to oxygen deficiency was illustrated, including induced oxidative response and immune defense and changed digestive enzymes activities, which could help to develop a better understanding of the responsive mechanism of sea cucumber under hypoxia stress. Expand
Carbohydrate and amino acids metabolic response to heat stress in the intestine of the sea cucumber Apostichopus japonicus
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This study studied the mRNA expression profiles of eight key metabolic enzymes involved in carbohydrate and amino acids metabolism in A. japonicus under heat stress to suggest significant links between gene expression and metabolites changing, highlighting regulation networks of carbohydrates and amino acid metabolism in heat-stressed A. Japonicus. Expand
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Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress
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Investigation of alterations in miRNA expression in the sea cucumber under different levels of dissolved oxygen suggested that these miRNAs are important in redox, transport, transcription, and hydrolysis under hypoxia stress. Expand
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