Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae.

@article{Wisselink2010MetabolomeTA,
  title={Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae.},
  author={H. Wouter Wisselink and Chiara Cipollina and Bart Oud and Barbara Crimi and Joseph J. Heijnen and Jack T. Pronk and Antonius J. A. van Maris},
  journal={Metabolic engineering},
  year={2010},
  volume={12 6},
  pages={537-51}
}
One of the challenges in strain improvement by evolutionary engineering is to subsequently determine the molecular basis of the improved properties that were enriched from the natural genetic variation during the selective conditions. This study focuses on Saccharomyces cerevisiae IMS0002 which, after metabolic and evolutionary engineering, ferments the pentose sugar arabinose. Glucose- and arabinose-limited anaerobic chemostat cultures of IMS0002 and its non-evolved ancestor were subjected to… CONTINUE READING
35 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…