Metabolites of 6-[18F]fluoro-L-dopa in human blood.

@article{Firnau1988MetabolitesO6,
  title={Metabolites of 6-[18F]fluoro-L-dopa in human blood.},
  author={Gunter Firnau and Sandeep Sood and Raman V Chirakal and Claude Nahmias and E. Stephen Garnett},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1988},
  volume={29 3},
  pages={
          363-9
        }
}
The metabolites of 6-[18F]fluoro-L-dopa in the blood plasma of healthy humans have been identified as 3-O-sulfato-6[18F]fluoro-L-dopa, 3-O-methyl-6-[18F]fluoro-L-dopa, 6-[18F] fluorodopamine, and 6-[18F]fluorohomovanillic acid. The time course of these metabolites was followed up to 2 hr. The findings have implications for the use of 6-[18F]fluoro-L-dopa as tracer for cerebral dopamine metabolism. Despite the variety of metabolites in the peripheral blood there are only two 18F-carrying… CONTINUE READING

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