Metabolism study of hesperetin and hesperidin in rats by UHPLC-LTQ-Orbitrap MS n

@article{Jiao2019MetabolismSO,
  title={Metabolism study of hesperetin and hesperidin in rats by UHPLC-LTQ-Orbitrap MS n},
  author={Qi-Shu Jiao and Lulu Xu and Lijuan Jiang and Y. Jiang and Jia-yu Zhang and B. Liu},
  journal={Xenobiotica},
  year={2019},
  volume={50},
  pages={1311 - 1322}
}
Abstract Hesperidin (HPD) and hesperetin (HPT), as a kind of flavonone compounds, are abundant in citrus fruits with various pharmacological effects. HPD and HPT are not always consistent in some biological activities, even if they have the same skeletal structure. The aim of this study was to screen and identify HPT and HPD metabolites in rats using UHPLC-LTQ-Orbitrap MS n , compare the possible metabolism and provide the research basis for further understanding the similarities and… Expand

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