Metabolism of the polycyclic aromatic hydrocarbon pyrene by Aspergillus niger SK 9317

@article{Wunder1994MetabolismOT,
  title={Metabolism of the polycyclic aromatic hydrocarbon pyrene by Aspergillus niger SK 9317},
  author={Thomas Wunder and Stefan Kremer and Olov Sterner and Heidrun Dr. Anke},
  journal={Applied Microbiology and Biotechnology},
  year={1994},
  volume={42},
  pages={636-641}
}
The metabolism of pyrene, a polycyclic aromatic hydrocarbon consisting of four rings, by Aspergillus niger SK 9317 was investigated. The metabolites formed were isolated and identified as 1-hydroxypyrene, 1,6- and 1,8-pyrenequinone, 1,6- and 1,8-dihydroxypyrene, 1-pyrenyl sulphate and 1-hydroxy-8-pyrenyl sulphate. This is the first report of 1-hydroxy-8-pyrenyl as a metabolite in the microbial metabolism of pyrene. The results suggest that A. niger metabolizes pyrene by cytochrome P-450… CONTINUE READING
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