Metabolism of the folate precursor p-aminobenzoate in plants: glucose ester formation and vacuolar storage.

@article{Eudes2008MetabolismOT,
  title={Metabolism of the folate precursor p-aminobenzoate in plants: glucose ester formation and vacuolar storage.},
  author={Aymerick Eudes and Gale G. Bozzo and Jeffrey C. Waller and Valeria Naponelli and E S Lim and Dianna J. Bowles and J. Gregory and Andrew D. Hanson},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 22},
  pages={15451-9}
}
Plants produce p-aminobenzoate (pABA) in chloroplasts and use it for folate synthesis in mitochondria. In plant tissues, however, pABA is known to occur predominantly as its glucose ester (pABA-Glc), and the role of this metabolite in folate synthesis has not been defined. In this study, the UDP-glucose:pABA acyl-glucosyltransferase (pAGT) activity in Arabidopsis extracts was found to reside principally (95%) in one isoform with an apparent K(m) for pABA of 0.12 mm. Screening of recombinant… CONTINUE READING

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