Metabolism of sulpiride in man and rhesus monkeys.


The metabolism of 14C-carbonyl-sulpiride (form A) and of 14C-3, 4 pyrrolidine-sulpiride (form B) was studied in the rhesus monkey and man. In the monkey, the metabolites in both the urine and the bile were the same with form A and form B: 60-80% sulpiride, 10-30% 5-oxopyrrolidine sulpiride and 3-8% an unidentified metabolite (ME-X). In four human volunteers… (More)


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@article{Imondi1978MetabolismOS, title={Metabolism of sulpiride in man and rhesus monkeys.}, author={Anthony R. Imondi and Ahmed Shafin Alam and J. J. Brennan and Larry M. Hagerman}, journal={Archives internationales de pharmacodynamie et de therapie}, year={1978}, volume={232 1}, pages={79-91} }