Metabolism of styrene oxide in different human fetal tissues.

  title={Metabolism of styrene oxide in different human fetal tissues.},
  author={Gian Maria Pacifici and Anders Rane},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  volume={10 4},
Epoxide hydrolase and glutathionetransferase activities toward [7-3H]styrene 7,8-oxide were measured in the microsomal and cytosolic fractions, respectively, of human fetal liver, lungs, kidneys, adrenal glands, gut, and placenta. Both activities were present at significant rates in all the tissue specimens studied. Epoxide hydrolase activities in the liver… CONTINUE READING