Metabolism of rat brain mitochondria. Studies on the potassium ion-stimulated oxidation of pyruvate.

Abstract

1. Rat brain-cortex mitochondria were incubated in media containing 1, 5 or 100mm-K(+) in the presence of ADP, uncoupler (FCCP, carbonyl cyanide p-trifluoro-methoxyphenylhydrazone) or valinomycin while metabolizing pyruvate and malate, or acetylcarnitine and malate or glutamate and malate as substrates. Both the uptake of oxygen and disappearance of… (More)

Topics

10 Figures and Tables

Cite this paper

@article{Nicklas1971MetabolismOR, title={Metabolism of rat brain mitochondria. Studies on the potassium ion-stimulated oxidation of pyruvate.}, author={William J. Nicklas and John Bates Clark and Joseph R. Williamson}, journal={The Biochemical journal}, year={1971}, volume={123 1}, pages={83-95} }