Metabolism of psilocybin and psilocin: clinical and forensic toxicological relevance

  title={Metabolism of psilocybin and psilocin: clinical and forensic toxicological relevance},
  author={R. Dinis-Oliveira},
  journal={Drug Metabolism Reviews},
  pages={84 - 91}
  • R. Dinis-Oliveira
  • Published 2017
  • Medicine, Chemistry
  • Drug Metabolism Reviews
  • Abstract Psilocybin and psilocin are controlled substances in many countries. These are the two main hallucinogenic compounds of the “magic mushrooms” and both act as agonists or partial agonists at 5-hydroxytryptamine (5-HT)2A subtype receptors. During the last few years, psilocybin and psilocin have gained therapeutic relevance but considerable physiological variability between individuals that can influence dose-response and toxicological profile has been reported. This review aims to… CONTINUE READING


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